Fishing the river in spring is a great opportunity but there have not been any recent fishing reports. Ana River is a great match-the-hatch fly-fishing river with good hatches throughout the year. Hatches typically occur during the afternoon from 12-3 p.m. Small blue-winged olive mayfly hatches are typically best on overcast days with light rain. Beadheads under a bobber work as well as stripping minnow patterns in low light conditions.

Tui chub are abundant in the river therefore casting large flies or lures can be effective for catching larger fish. Bait fishing is allowed and anglers can keep 5 trout. Early this spring an angler caught a hybrid bass in the river, which happens occasionally.