The Applegate River is open for trout fishing. This is mainly a catch and release fishery for cutthroat. Cutthroat trout can be found hanging out in the deep pools spread throughout the river but are more numerous upstream of the town of Applegate where the water is colder. Only adipose fin clipped rainbow trout may be retained. All wild rainbow and cutthroat trout must be released unharmed. Consult the fishing regulations for more information. Anglers are encouraged to harvest any pikeminnow caught in the Applegate, while releasing native suckers unharmed.